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Alzheimer's Association

Alzheimer's Disease Education & Referral Center

Alzheimer's Foundation of America

Association for the Frontotemporal Degeneration

Cognitive Dynamics
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Autism Society of America
1-800-3AUTISM (1-800-328-8476)

Autism Speaks Inc.
(212) 252-8584

Global & Regional Asperger Syndrome Partnership

United Cerebral Palsy

American Dystonia Society

Citizens United for research in Epilepsy (CURE)
(312) 255-1801

Epilepsy Foundation

Epilepsy Therapy Project
(540) 687-8077


American Headache Society Committee for Headache Education (ACHE)
(856) 423-0043

Migraine Research Foundation
(212) 249-5402

National Headache Foundation

Hereditary Disease Foundation
(212) 928-2121

Huntington's Disease Society of America

Encephalitis Global



Multiple Sclerosis Association of America

Multiple Sclerosis Foundation

National Multiple Sclerosis Society
1-800-FIGHT-MS (1-800-344-4867)

American Academy of Neurology

American Brain Foundation
1-800-879-1960 (same as above # !)

(Free personalized Web Site to support your health journey!)
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National Institute of Neurological Disorders & Stroke

Well Spouse Association

American Pain Foundation
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American Parkinson Disease Association

Foundation for PCP, CBD, & Related Brain Diseases

International Essential Tremor Foundation

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Lewy Body Dementia Association
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Parkinson's Disease Foundation

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We Move
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National Sleep Foundation
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International Disability Coalition

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Transverse Myelitis Association
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Living with TN

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Brain Trauma Foundation
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Coffee: A Cyber Serving: 
Do you drink too much coffee?  It's a fact, that in the 1700's the french philosopher "Voltaire" reportedly downed 50 cups a day.  Legend has it that when others denounced the brew as a poison, Voltaire retorted, "I have been poisoning myself for more than 80 years, and I am not yet dead." Nor is the debate over coffee's effects or how to bre a perfect cup...Get a sip of this HOT topic by clicking here: 

Moral 2 the story:

Are you sure you’re allergic to penicillin?

Published by Scott Gavura 

As a pharmacist, when I dispense medication, it’s my responsibility to ensure that the medication is safe and appropriate for the patient. There are numerous checks we go through including verifying the dose, ensuring there are no interactions with other drugs, and verifying the patient has no history of allergy to the product prescribed. Asking about allergies is a mandatory question for every new patient.

Penicillin is one of the oldest antibiotics still in use despite widespread bacterial resistance. Multiple analogs of penicillin have been developed to change its effectiveness, or improve its tolerability. And other classes of antibiotics (e.g., cephalosporins) share some structural features with penicillin. These products are widely used for both routine and serious bacterial infections. Unfortunately, allergies to penicillin are widely reported. Statistically, one in ten of you reading this post will respond that you’re allergic to penicillin. Yet the incidence of anaphylaxis to penicillin is estimated to be only 1 to 5 per 10,000. So why do so many people believe they’re allergic to penicillin? Much of it comes down to how we define “allergy.”

Adverse Events, Reactions, and Allergies

There are a number of confounders when it comes to evaluating allergies. A big one is terminology. While different groups vary in their definitions, the term “adverse drug event” typically means that an undesirable event has occurred, but isn’t causally linked to the consumption of a drug. In contrast, “adverse drug reaction” is usually reserved to where a causal link to the drug has been established, or is fairly certain. Adverse drug reactions can occur under completely normal use of a drug. And they’re not uncommon, as I’ve pointed out before. An allergic reaction to a drug is an adverse drug reaction that is mediated by an immune response. If there is no immune response, it’s not an allergic reaction. So if you take codeine and it makes you drowsy and constipated, that’s not an allergic reaction—that’s an effect of the drug. Erythromycin commonly causes stomach upset, so if you vomit, that’s not an allergy either. So, to sum:

Penicillin Allergies:

Within that box of adverse reactions we’re calling “drug allergies” there’s a number of methods of classifying the different immune responses. The most common way is to split events into immunoglobulin E (IgE)–mediated (immediate) reactions, or non–IgE-mediated (delayed) hypersensitivity reactions. The IgE-mediated reactions are the ones we might immediately think of when we hear “penicillin allergy”: flushing, itchy skin, wheezing, vomiting, throat swelling, and even anaphylaxis. These reactions can occur immediately to a few hours after a dose. The non-IgE-mediated reactions are delayed, and can be mild or severe, ranging from serum sickness to the horrific (but fortunately rare) Stevens-Johnson syndrome.

Skin rash (morbilliform eruptions) are non-IgE reactions commonly reported with penicillin therapy, though their relationship to the penicillin itself isn’t clear. Rashes that appears several days after starting therapy (or even after finishing a course of antibiotics) may be due to a poorly-understood relationship between the antibiotic and any concurrent viral infection. These rashes are not itchy. With subsequent exposure to penicillin (or a related drug) the rash can reappear. These types of reactions do not mean that one cannot receive penicillin again, however.

It’s the structure of the penicillin molecule itself that triggers allergic reactions. Both the “parent” drug and any iterations created through metabolism can induce allergic responses. Analogs of penicillin, with different molecular side chains, can trigger selective sensitivity in some. So one could have an allergic reaction to amoxicillin or ampicillin, but be able to tolerate penicillin.

Testing for allergies:

Determining if you’re actually allergic to penicillin is important to sort out, as not all reactions mean penicillin cannot be administered again. Skin testing is the standard for testing for IgE-mediated allergies, and needs to be performed under medical supervision, usually by allergy specialists, in settings where access to resuscitation medication is available. Given the unreliability of memory, skin testing is the standard when there’s any doubt all about the type of prior reaction. In cases of the severe non-Ig-E type reactions, there’s no rechallenge attempted, and those patients should never receive penicillins again.

So if you think you’re allergic to penicillin, but are not certain of the type of allergy you have, testing is something worth thinking about. Without it, you’re setting yourself up for a lifetime of risk and consequences of the avoidance of penicillin. Data show that patients considered penicillin-allergic will typically receive more broad-spectrum antibiotics, which may have more side effects, be more expensive, and in some situations, less effective. And given IgE-mediated allergy can wane over time, even significant childhood reactions may not manifest as adult allergies—but only testing can determine this for certain.

Formal evaluations of penicillin allergies support this approach. A recent paper in the Journal of Allergy and Clinical Immunology describes a prospective evaluation of children that presented to an emergency room with a delayed-onset rash from penicillin. Eighty-eight children were enrolled over two years. At the time of enrollment, they were screened for viruses. Each child returned to the hospital two months after their initial visit, where they underwent skin (patch and intradermal) as well as blood evaluations for allergy. They all had an oral challenge with the original antibiotic, too. After evaluation, none had a positive skin test, 11 children (12.5%) had a intradermal reaction, and only six (6.8%) had the rash recur after an oral challenge. Within the group that had a positive oral challenge, two had intradermal-negative, and one was intradermal-positive. Most of the children had tested positive for viral infections, too.

The authors concluded that penicillin allergies are overdiagnosed, and viral infections may be a factor leading to rashes and over-diagnosis. The authors recommended oral challenges, rather than skin, intradermal, or blood tests for all children that develop delayed-onset rashes during treatment with penicillins.


While penicillin allergies can be real, and can be serious, only a small percentage of people that consider themselves allergic actually cannot receive penicillin. Avoiding penicillin can mean using antibiotic alternatives that are less effective, more expensive, and have greater side effects. For this reason, confirming a penicillin allergy with a physician is warranted—before an antibiotic is needed. After all, unless it’s necessary, you don’t want to end up with someone like Mark Crislip standing over your hospital bed, being asked what his second choice of antibiotic is going to be.

Caubet JC, Kaiser L, Lemaître B, Fellay B, Gervaix A, & Eigenmann PA (2011). The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge. The Journal of allergy and clinical immunology, 127 (1), 218-22.

(Now, these days, please consider to use a Vapor cigarette!)CLICK HERE!

"13 Health Rules You Can Break" says's Brian Krans

Mother Wasn’t Always Right...Either is Brian Krans, please, tell me something I don't know!!!
The myth is that this habit will cause arthritis...Don't all (dumb)habits have (stupid) myths, that will cause something, possibly one may die from; if we don't get hit by a car while crossing the road, or struck by lightening...It may be annoying, but pays me for these type medical studies that prove healthy habits are better than nothing. The habit of cracking or popping your fingers will lead to arthritis. However, some doctors say cracking your knuckles repeatedly may hurt your fingers in other ways (besides driving your coworkers crazy), so it's best to avoid the habit. Ever wondered where the popping sound comes from? When you stretch your fingers you pull the bones, creating an air bubble around the joints. When the bubble bursts, it makes a sound.

1.) Don't Crack Your Knuckles

The myth is that this habit will cause arthritis. It may be annoying, but no medical studies prove cracking or popping your fingers will lead to arthritis. However, some doctors say cracking your knuckles repeatedly may hurt your fingers in other ways (besides driving your coworkers crazy), so it's best to avoid the habit. Ever wonder where the popping sound comes from? When you stretch your fingers you pull the bones, creating an air bubble around the joints. When the bubble bursts, it makes a sound.

2.)Don't Go Outside With Wet Hair

It may make you feel chilly (wet hair doesn't insulate well), but it won't make you sick. Colds are caused by a virus that is usually spread by droplets from someone's cough or sneeze. To avoid the virus, you're better off washing your hands often and avoiding crowded places or close contact with someone who's sick. What makes you more vulnerable to a cold virus: fatigue, stress, and certain bad allergies.

3.)Don't Swim After You Eat

Sorry, Mom, but there's no evidence that this causes cramps, which could possibly lead to drowning. While it's true that eating diverts some blood to the digestive system, most experts agree your body can still provide enough blood and oxygen during exercise to keep cramps from happening. Eating a big meal may make you feel too full to knock out a bunch of laps, but it won't make you drown.

4.)Drink Eight Cups of Water a Day

As long as you're drinking enough so that you don't feel thirsty, you urinate often, and your urine is nearly colorless, you're probably getting enough water. And remember that magic "eight cups a day" includes water you get from foods and other beverages, and those help you gain other nutrients, too. While water is necessary, some healthy alternatives to H20 include broth-based soups and water-laden produce such as grapes, cucumbers, and melon.

5.)Avoid Reading in Dim Light

You may get a headache and strain your eyes, but experts say poor lighting will not cause permanent damage to your eyesight. Ditto for sitting too close to a television or computer screen. To reduce eye strain, sit at a comfortable distance and take breaks often—at least every 20 minutes.

6.)Use Birth Control That Follows Your Monthly Cycle

Traditional birth control pills are based on a 28-day cycle. The pills have reproductive hormones you take for the first 21 days, followed by a placebo for the next seven days, during which you have your period. In the past, doctors sometimes adjusted the dosage for women with painful or heavy periods. But with the advent of extended-cycle birth control pills, you can skip your period altogether or have it just a few times a year. Talk to your doctor to see which option is right for you.

7.)Sugar Makes Kids Hyper

While too much of it will cause teeth problems, it’s a common myth that sugar creates hyperactivity in children. This theory was tested in a variety of children, including those believed to be sensitive to sugar. Research found that although children consumed well over their average daily intake, neither table sugar or aspartame—an artificial sweetener—negatively affected the children’s behavior. Other research confirmed these findings. 

8.)The ’Five-Second’ Rule

We’ve all heard this one when someone scoops food off the floor, as if germs stand by with a stopwatch to wait to latch onto food. In 2004, a college student named Jillian Clarke tested this theory and found that it was nothing but a myth. However, her research found that food dropped on carpet attracted fewer germs (but more cat hair) than if dropped on a hard surface.

9.)‘Feed a Cold, Starve a Fever’

This has been an English wives tale for centuries, but there’s no concrete evidence to support it. One study found that food and starvation both produced a response from the immune system. When it comes to illness, drinking plenty of fluids is key to a quick recovery. As a general rule, if you’re hungry—the way your body tells you it needs nutrition—you should probably eat.

10.) Don’t Drink Caffeine or You’ll Be Dehydrated

People living in warm climates are usually warned not to consume too much caffeine because of its diuretic properties (a.k.a. it makes you pee), which could lead to dehydration. A 2002 study from the University of Connecticut, which has since been confirmed by others, showed that people who drank decaffeinated beverages only had a three percent difference in water retention, thus showing that caffeine and caffeinated beverages don’t cause dehydration.

11.) You Need 8 Hours of Sleep a Night

Not everyone needs eight hours of sleep a night. Some people run fine on six while others can barely function without nine. In fact, there’s historical evidence that humans used to sleep in intervals: two hours at dusk, a two-hour waking period, and then a second sleep. The amount of sleep you need varies on a variety of factors, including illness, stress, physical activity, and more. As a good rule, if you awake feeling tired, you probably need more or better sleep.

12.) Warm Milk Will Help You Sleep

Yes, milk contains tryptophan, the same sedative found in turkey, but you’d have to drink a few cows’ worth to knock you out for the night. The response people feel from it is entirely psychological, so it can help you fall asleep if you think it will. It has the same comforting effect as wrapping up for the night with your teddy bear.

13.) Gum Stays in Your Stomach for 7 Years

Every child who has swallowed his gum has heard this one. Chewing gum, just like anything else you swallow, will get picked up by the fluids and other food in your stomach and move it through digestion. It doesn’t even take seven dogs years to get through. It usually only needs a few days at most, just like everything else.

7 Dangerous acts after a meal~

1. Don’t smoke —- Experiments from experts proves that smoking a cigarette after meal is comparable to smoking 10 cigarettes (chances of cancer is higher)

2. Don’t eat fruits immediatelyImmediately eating fruits after meals will cause stomach to be bloated with air. Therefore take fruits 1 -2 hours after meal or 1 hour before meal.

3. Don’t drink tea—— Because tea leaves, contain a high content of acid. This substance will cause the protein content in the food we consume to be difficult to digest.

4. Don’t loosen your belt
—— Loosening the belt after meal will easily cause the intestine to be twisted and blocked.

5. Don’t bathe——Bathing after meal will cause the increase of blood flow to the hands, legs and body thus the amount of blood around the stomach will therefore decrease, this will weaken the digestive system in our stomach.

6. Don’t walk about
——People always say that after a meal walk a hundred steps and you will live till 99. In actuality, this fact is not true. Walking will cause the digestive system to be unable to absorb the nutrition from the food we intake.

7. Don’t sleep immediately
The food we intake will not be to digest properly; Thus it will lead to gastric and infection in our intestines.

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